Regulation of F-Actin Bundles by Triobp-4
نویسندگان
چکیده
منابع مشابه
F-Actin Bundles Are Derivatives of Microvilli
Fruit fly bristles have us tearing out our few remaining hairs. The puzzle is, in forming long bristles, how and why do flies assemble long actin bundles by gluing shorter bundles end-to-end? Fruit fly bristles extend posteriorly in a gentle curve over the fly's back like the hair on a well-groomed individual from the 60's. These bristles, which are cellular extensions of 70 m in the microcha...
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Attractions between like-charged polyelectrolytes have been observed in a variety of systems (W.M. Gelbart, R.F. Bruinsma, P.A. Pincus, V.A. Parsegian, Phys. Today 53, September issue, 38 (2000)). Recent biological examples include DNA, filamentous viruses, and F-actin. Theoretical investigations on idealized systems indicate that counterion correlations play a central role, but no experiments ...
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In the presence of condensing agents such as nonadsorbing polymer, multivalent counter ions, and specific bundling proteins, chiral biopolymers typically form bundles with a finite thickness, rather than phase-separating into a polymer-rich phase. Although short-range repulsive interactions or geometrical frustrations are thought to force the equilibrium bundle size to be limited, the precise m...
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Inner ear hair cells detect sound through deflection of mechanosensory stereocilia. Each stereocilium is supported by a paracrystalline array of parallel actin filaments that are packed more densely at the base, forming a rootlet extending into the cell body. The function of rootlets and the molecules responsible for their formation are unknown. We found that TRIOBP, a cytoskeleton-associated p...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.2048